InnateDB Protein
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IDBP-586253.3
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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PAFAH1B2
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Protein Name
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platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
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Synonyms
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HEL-S-303;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000435289
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InnateDB Gene
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IDBG-73009 (PAFAH1B2)
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Protein Structure
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|
Function |
Inactivates PAF by removing the acetyl group at the sn-2 position. This is a catalytic subunit.
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Subcellular Localization |
Cytoplasm.
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Disease Associations |
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Tissue Specificity |
Ubiquitous. {ECO:0000269PubMed:9144386}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 41 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated |
Total |
41
[view]
|
Protein-Protein |
41
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
|
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Predicted by orthology |
Total |
3 [view]
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|
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Molecular Function |
Accession |
GO Term |
GO:0003847
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1-alkyl-2-acetylglycerophosphocholine esterase activity
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GO:0005515
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protein binding
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GO:0016788
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hydrolase activity, acting on ester bonds
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GO:0042803
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protein homodimerization activity
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GO:0046982
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protein heterodimerization activity
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR001087
Lipase, GDSL
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PFAM |
PF00657
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
P68402
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PhosphoSite |
PhosphoSite-P68402
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TrEMBL |
V9HW44
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UniProt Splice Variant |
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Entrez Gene |
5049
|
UniGene |
Hs.743251
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RefSeq |
NP_002563
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HUGO |
HGNC:8575
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OMIM |
602508
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CCDS |
CCDS8380
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HPRD |
03940
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IMGT |
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EMBL |
AK292973
AP005018
BC000398
BC019301
CH471065
CR456736
D63390
DQ836738
DQ836739
DQ836740
DQ836741
DQ836742
DQ836743
EF445007
FJ224328
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GenPept |
AAH00398
AAH19301
ABI58225
ABI58226
ABI58227
ABI58228
ABI58229
ABI58230
ACA06040
ACI46020
BAA19917
BAF85662
CAG33017
EAW67281
EAW67282
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