InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: RSAD1

Summary

InnateDB Protein

IDBP-58626.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

RSAD1

Protein Name

radical S-adenosyl methionine domain containing 1

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000258955

InnateDB Gene

IDBG-58624 (RSAD1)

Protein Structure

UniProt Annotation

Function

May be involved in porphyrin cofactor biosynthesis. {ECO:0000250}.

Subcellular Localization

Mitochondrion {ECO:0000305}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0004109	coproporphyrinogen oxidase activity
GO:0046872	metal ion binding
GO:0051536	iron-sulfur cluster binding
GO:0051539	4 iron, 4 sulfur cluster binding

Biological Process

GO:0006779	porphyrin-containing compound biosynthetic process
GO:0055114	oxidation-reduction process

Cellular Component

GO:0005737	cytoplasm
GO:0005739	mitochondrion

Protein Structure and Domains

PDB ID

InterPro

IPR004559 Coproporphyrinogen III oxidase, oxygen-independent related
IPR006638 Elongator protein 3/MiaB/NifB
IPR007197 Radical SAM
IPR010723 HemN, C-terminal domain

PFAM

PF04055
PF06969

PRINTS

PIRSF

SMART

SM00729

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q9HA92