Homo sapiens Protein: GLI1
Summary
InnateDB Protein IDBP-586421.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GLI1
Protein Name GLI family zinc finger 1
Synonyms GLI;
Species Homo sapiens
Ensembl Protein ENSP00000437607
InnateDB Gene IDBG-42577 (GLI1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 41 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Experimentally validated
Total 41 [view]
Protein-Protein 32 [view]
Protein-DNA 5 [view]
Protein-RNA 0
DNA-DNA 4 [view]
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0044212 transcription regulatory region DNA binding
GO:0046872 metal ion binding
Biological Process
GO:0001649 osteoblast differentiation
GO:0007224 smoothened signaling pathway
GO:0008284 positive regulation of cell proliferation
GO:0008589 regulation of smoothened signaling pathway
GO:0009913 epidermal cell differentiation
GO:0045087 innate immune response (InnateDB)
GO:0045740 positive regulation of DNA replication
GO:0045880 positive regulation of smoothened signaling pathway
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0048546 digestive tract morphogenesis
GO:0090090 negative regulation of canonical Wnt signaling pathway
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0043231 intracellular membrane-bounded organelle
Protein Structure and Domains
PDB ID
InterPro IPR007087 Zinc finger, C2H2
IPR015880 Zinc finger, C2H2-like
PFAM PF00096
PRINTS
PIRSF
SMART SM00355
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P08151
PhosphoSite PhosphoSite-P08151
TrEMBL E9PIB9
UniProt Splice Variant
Entrez Gene 2735
UniGene Hs.632702
RefSeq NP_001153517
HUGO HGNC:4317
OMIM 165220
CCDS CCDS53807
HPRD 01311
IMGT
EMBL AC022506 AF316573 BC013000 GQ890670 X07384
GenPept AAH13000 AAM13391 ACX35434 CAA30297