Version 5.4
Homo sapiens Protein: TWF1
Summary
InnateDB Protein IDBP-586982.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TWF1
Protein Name twinfilin, actin-binding protein, homolog 1 (Drosophila)
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000448221
InnateDB Gene IDBG-28090 (TWF1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 26 experimentally validated interaction(s) in this database.
Experimentally validated
Total 26 [view]
Protein-Protein 26 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
Biological Process
GO:0030837 negative regulation of actin filament polymerization
Cellular Component
GO:0005622 intracellular
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR002108 Actin-depolymerising factor homology domain
PFAM PF00241
PRINTS
PIRSF
SMART SM00102
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL F8VS81
UniProt Splice Variant
Entrez Gene 5756
UniGene Hs.313056
RefSeq
HUGO HGNC:9620
OMIM 610932
CCDS
HPRD 10174
IMGT
EMBL AC093012
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca