InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: OTX2

Summary

InnateDB Protein

IDBP-587625.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

OTX2

Protein Name

orthodenticle homeobox 2

Synonyms

CPHD6; MCOPS5;

Species

Homo sapiens

Ensembl Protein

ENSP00000451357

InnateDB Gene

IDBG-7551 (OTX2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.

Experimentally validated
Total	7 [view]
Protein-Protein	7 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	9 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0043565	sequence-specific DNA binding

Biological Process

GO:0007275

multicellular organismal development

Cellular Component

GO:0005634

nucleus

Protein Structure and Domains

PDB ID

InterPro

IPR001356 Homeobox domain
IPR003022 Transcription factor Otx2
IPR003025 Transcription factor Otx
IPR009057 Homeodomain-like
IPR013851 Transcription factor Otx, C-terminal

PFAM

PF00046
PF03529

PRINTS

PR01257
PR01255

PIRSF

SMART

SM00389

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt