Version 5.4
Homo sapiens Protein: CFL1
Summary
InnateDB Protein IDBP-588120.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CFL1
Protein Name cofilin 1 (non-muscle)
Synonyms CFL; HEL-S-15;
Species Homo sapiens
Ensembl Protein ENSP00000431696
InnateDB Gene IDBG-57818 (CFL1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 95 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 95 [view]
Protein-Protein 92 [view]
Protein-DNA 3 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003779 actin binding
Biological Process
GO:0030042 actin filament depolymerization
Cellular Component
GO:0005622 intracellular
GO:0015629 actin cytoskeleton
Protein Structure and Domains
PDB ID
InterPro IPR002108 Actin-depolymerising factor homology domain
IPR017904 ADF/Cofilin/Destrin
PFAM PF00241
PRINTS PR00006
PIRSF
SMART SM00102
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL G3V1A4
UniProt Splice Variant
Entrez Gene 1072
UniGene Hs.738283
RefSeq
HUGO HGNC:1874
OMIM 601442
CCDS
HPRD 03261
IMGT
EMBL AP001266 CH471076
GenPept EAW74448 EAW74450

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca