Homo sapiens Protein: PFKM
Summary
InnateDB Protein IDBP-588576.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PFKM
Protein Name phosphofructokinase, muscle
Synonyms ATP-PFK; GSD7; PFK-1; PFK1; PFKA; PFKX; PPP1R122;
Species Homo sapiens
Ensembl Protein ENSP00000449426
InnateDB Gene IDBG-29733 (PFKM)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 28 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 28 [view]
Protein-Protein 27 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003872 6-phosphofructokinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008022 protein C-terminus binding
GO:0019900 kinase binding
GO:0042802 identical protein binding
GO:0046872 metal ion binding
GO:0070061 fructose binding
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0006002 fructose 6-phosphate metabolic process
GO:0006006 glucose metabolic process
GO:0006096 glycolytic process
GO:0044281 small molecule metabolic process
GO:0046716 muscle cell cellular homeostasis
GO:0046835 carbohydrate phosphorylation
GO:0051259 protein oligomerization
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005945 6-phosphofructokinase complex
GO:0016324 apical plasma membrane
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR000023 Phosphofructokinase domain
IPR009161 6-phosphofructokinase, eukaryotic type
IPR022953 Phosphofructokinase
PFAM PF00365
PRINTS PR00476
PIRSF PIRSF000533
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P08237
PhosphoSite PhosphoSite-P08237
TrEMBL Q7KYX9
UniProt Splice Variant
Entrez Gene 5213
UniGene Hs.75160
RefSeq NP_001160160
HUGO HGNC:8877
OMIM 610681
CCDS CCDS8760
HPRD 01988
IMGT
EMBL AC004801 AC074029 AH002936 AK126229 BC000534 BC012799 BC013298 BC021203 CH471111 CR541698 J05533 M24925 M26066 M59720 M59721 M59722 M59723 M59724 M59725 M59726 M59727 M59728 M59729 M59730 M59731 M59732 M59733 M59734 M59735 M59736 M59737 M59738 M59739 M59740 M59741 U24183 Y00698
GenPept AAA36436 AAA60068 AAA60069 AAA79220 AAA82938 AAA91985 AAH00534 AAH12799 AAH13298 AAH21203 BAC86498 CAA68692 CAG46499 EAW57974 EAW57975