Version 5.4
Homo sapiens Protein: STRN4
Summary
InnateDB Protein IDBP-58965.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol STRN4
Protein Name striatin, calmodulin binding protein 4
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000263280
InnateDB Gene IDBG-58963 (STRN4)
Protein Structure
UniProt Annotation
Function Binds calmodulin in a calcium dependent manner. May function as scaffolding or signaling protein.
Subcellular Localization Cytoplasm {ECO:0000250}. Membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Cell projection, dendritic spine {ECO:0000250}. Note=CTTNBP2-binding may regulate dendritic spine distribution. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 81 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 81 [view]
Protein-Protein 81 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0005516 calmodulin binding
GO:0032403 protein complex binding
GO:0051721 protein phosphatase 2A binding
GO:0070016 armadillo repeat domain binding
Biological Process
GO:0008150 biological_process
Cellular Component
GO:0000159 protein phosphatase type 2A complex
GO:0005737 cytoplasm
GO:0016020 membrane
GO:0043197 dendritic spine
Protein Structure and Domains
PDB ID
InterPro IPR001680 WD40 repeat
IPR013258 Striatin, N-terminal
IPR017986 WD40-repeat-containing domain
IPR020472 G-protein beta WD-40 repeat
PFAM PF00400
PF08232
PRINTS PR00320
PIRSF
SMART SM00320
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9NRL3
PhosphoSite PhosphoSite-Q9NRL3
TrEMBL M0R2A7
UniProt Splice Variant
Entrez Gene 29888
UniGene Hs.631590
RefSeq NP_037535
HUGO HGNC:15721
OMIM 614767
CCDS CCDS12690
HPRD 18125
IMGT
EMBL AC008622 AC008635 AF212940 AK056294 BC004910 BC034604 CH471126
GenPept AAF29527 AAH04910 AAH34604 BAG51668 EAW57442 EAW57443

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca