Version 5.4
Homo sapiens Protein: ORC3
Summary
InnateDB Protein IDBP-590064.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ORC3
Protein Name origin recognition complex, subunit 3
Synonyms LAT; LATHEO; ORC3L;
Species Homo sapiens
Ensembl Protein ENSP00000444695
InnateDB Gene IDBG-94195 (ORC3)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 47 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 47 [view]
Protein-Protein 44 [view]
Protein-DNA 3 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003688 DNA replication origin binding
GO:0005515 protein binding
Biological Process
GO:0000082 G1/S transition of mitotic cell cycle
GO:0000278 mitotic cell cycle
GO:0006260 DNA replication
Cellular Component
GO:0000808 origin recognition complex
GO:0005654 nucleoplasm
GO:0005664 nuclear origin of replication recognition complex
Protein Structure and Domains
PDB ID
InterPro IPR020795 Origin recognition complex, subunit 3
PFAM PF07034
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9UBD5
PhosphoSite PhosphoSite-Q9UBD5
TrEMBL U3KQL3
UniProt Splice Variant
Entrez Gene 23595
UniGene Hs.735758
RefSeq NP_001184188
HUGO HGNC:8489
OMIM 604972
CCDS CCDS56440
HPRD 05398
IMGT
EMBL AF093535 AF125507 AF135044 AK222795 AK303195 AK315911 AL080116 AL133211 AL451126 AY623113 BC035494 BC047689 U50950
GenPept AAA96313 AAD18057 AAD30282 AAD40220 AAH35494 AAH47689 AAT38109 BAD96515 BAG64287 BAH14282 CAB45715 CAI10900 CAI21539 CAM13063 CAM28255

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca