Version 5.4
Homo sapiens Protein: PIP5K1B
Summary
InnateDB Protein IDBP-590084.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PIP5K1B
Protein Name phosphatidylinositol-4-phosphate 5-kinase, type I, beta
Synonyms MSS4; STM7;
Species Homo sapiens
Ensembl Protein ENSP00000438082
InnateDB Gene IDBG-69048 (PIP5K1B)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016307 phosphatidylinositol phosphate kinase activity
GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity
Biological Process
GO:0006644 phospholipid metabolic process
GO:0006661 phosphatidylinositol biosynthetic process
GO:0044281 small molecule metabolic process
GO:0046488 phosphatidylinositol metabolic process
GO:0046854 phosphatidylinositol phosphorylation
Cellular Component
GO:0001931 uropod
GO:0005829 cytosol
GO:0012505 endomembrane system
GO:0016020 membrane
Protein Structure and Domains
PDB ID
InterPro IPR002498 Phosphatidylinositol-4-phosphate 5-kinase, core
IPR016034 Phosphatidylinositol-4-phosphate 5-kinase, core, subgroup
PFAM PF01504
PRINTS
PIRSF
SMART SM00330
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O14986
PhosphoSite PhosphoSite-O14986
TrEMBL Q7KYT4
UniProt Splice Variant
Entrez Gene 8395
UniGene Hs.534371
RefSeq NP_001265182
HUGO HGNC:8995
OMIM 602745
CCDS CCDS65063
HPRD 04121
IMGT
EMBL AK292734 AK295587 AL162730 AL354794 AL356219 BC030587 CH471089 U52376 U52377 U52378 U52379 U52380 U52381 U52382 U52383 U52384 U52385 U52386 U52387 U78580 U78581 X92493
GenPept AAC50915 AAC50916 AAC51327 AAH30587 BAF85423 BAG58479 CAA63224 CAH71831 CAI12622 CAI12623 CAI12624 CAI12625 CAI14092 CAI14093 CAI14094 CAI14095 EAW62465

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca