Homo sapiens Protein: MLH1
Summary
InnateDB Protein IDBP-590445.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MLH1
Protein Name mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli)
Synonyms COCA2; FCC2; hMLH1; HNPCC; HNPCC2;
Species Homo sapiens
Ensembl Protein ENSP00000444286
InnateDB Gene IDBG-24600 (MLH1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 151 experimentally validated interaction(s) in this database.
Experimentally validated
Total 151 [view]
Protein-Protein 144 [view]
Protein-DNA 7 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005524 ATP binding
GO:0030983 mismatched DNA binding
Biological Process
GO:0006298 mismatch repair
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR013507 DNA mismatch repair protein, C-terminal
IPR020568 Ribosomal protein S5 domain 2-type fold
PFAM PF01119
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL E7EUC9
UniProt Splice Variant
Entrez Gene 4292
UniGene Hs.195364
RefSeq NP_001245202
HUGO HGNC:7127
OMIM 120436
CCDS CCDS54563
HPRD 00390
IMGT
EMBL AC006583 AC011816 AK302807 CH471055 EU188665 FJ940753
GenPept ABW69161 ACR33810 BAH13807 EAW64484