Version 5.4
Homo sapiens Protein: IGF1R
Summary
InnateDB Protein IDBP-591084.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol IGF1R
Protein Name insulin-like growth factor 1 receptor
Synonyms CD221; IGFIR; IGFR; JTK13;
Species Homo sapiens
Ensembl Protein ENSP00000454115
InnateDB Gene IDBG-31432 (IGF1R)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 118 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Experimentally validated
Total 118 [view]
Protein-Protein 116 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0045087 innate immune response (InnateDB)
Cellular Component
GO:0016020 membrane
Protein Structure and Domains
PDB ID
InterPro IPR000494 EGF receptor, L domain
IPR009030 Insulin-like growth factor binding protein, N-terminal
PFAM PF01030
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL H0YNR0
UniProt Splice Variant
Entrez Gene 3480
UniGene Hs.714162
RefSeq
HUGO HGNC:5465
OMIM 147370
CCDS
HPRD 00932
IMGT
EMBL AC055807 AC069029 AC118658 AC118660
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca