Version 5.4
Homo sapiens Protein: PRR13
Summary
InnateDB Protein IDBP-591232.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PRR13
Protein Name proline rich 13
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000448761
InnateDB Gene IDBG-36739 (PRR13)
Protein Structure
UniProt Annotation
Function Negatively regulates TSP1 expression at the level of transcription. This down-regulation was shown to reduce taxane- induced apoptosis. {ECO:0000269PubMed:16847352}.
Subcellular Localization Nucleus {ECO:0000269PubMed:16847352}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
Experimentally validated
Total 7 [view]
Protein-Protein 6 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9NZ81
PhosphoSite PhosphoSite-Q9NZ81
TrEMBL F8W1R5
UniProt Splice Variant
Entrez Gene 54458
UniGene
RefSeq
HUGO HGNC:24528
OMIM 610459
CCDS CCDS44899
HPRD 13211
IMGT
EMBL AC068889 AF217517 BC014257 BC016064 BC066943 BK005847 BX640962 CH471054 CR533459
GenPept AAF67628 AAH14257 AAH16064 AAH66943 CAE45980 CAG38490 DAA05782 EAW96703 EAW96704

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca