InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: GATA4

Summary

InnateDB Protein

IDBP-592775.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

GATA4

Protein Name

GATA binding protein 4

Synonyms

ASD2; TACHD; TOF; VSD1;

Species

Homo sapiens

Ensembl Protein

ENSP00000435712

InnateDB Gene

IDBG-7434 (GATA4)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 38 experimentally validated interaction(s) in this database.
They are also associated with 23 interaction(s) predicted by orthology.

Experimentally validated
Total	38 [view]
Protein-Protein	35 [view]
Protein-DNA	3 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	23 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0001076	RNA polymerase II transcription factor binding transcription factor activity
GO:0003677	DNA binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0003713	transcription coactivator activity
GO:0005515	protein binding
GO:0008134	transcription factor binding
GO:0008270	zinc ion binding
GO:0033613	activating transcription factor binding
GO:0043565	sequence-specific DNA binding
GO:0044212	transcription regulatory region DNA binding
GO:0070410	co-SMAD binding

Biological Process

GO:0001947	heart looping
GO:0003197	endocardial cushion development
GO:0003208	cardiac ventricle morphogenesis
GO:0003215	cardiac right ventricle morphogenesis
GO:0003281	ventricular septum development
GO:0003289	atrial septum primum morphogenesis
GO:0003290	atrial septum secundum morphogenesis
GO:0006355	regulation of transcription, DNA-templated
GO:0006366	transcription from RNA polymerase II promoter
GO:0007267	cell-cell signaling
GO:0007492	endoderm development
GO:0007596	blood coagulation
GO:0008584	male gonad development
GO:0010575	positive regulation vascular endothelial growth factor production
GO:0035054	embryonic heart tube anterior/posterior pattern specification
GO:0042493	response to drug
GO:0045087	innate immune response (InnateDB)
GO:0045766	positive regulation of angiogenesis
GO:0045893	positive regulation of transcription, DNA-templated
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0048617	embryonic foregut morphogenesis
GO:0051891	positive regulation of cardioblast differentiation
GO:0060413	atrial septum morphogenesis
GO:0060575	intestinal epithelial cell differentiation