Version 5.4
Homo sapiens Protein: EXD3
Summary
InnateDB Protein IDBP-593239.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol EXD3
Protein Name exonuclease 3'-5' domain containing 3
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000431859
InnateDB Gene IDBG-93338 (EXD3)
Protein Structure
UniProt Annotation
Function Possesses 3'-5' exoribonuclease activity. Required for 3'-end trimming of AGO1-bound miRNAs (By similarity). {ECO:0000250}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0008408 3'-5' exonuclease activity
GO:0046872 metal ion binding
Biological Process
GO:0090305 nucleic acid phosphodiester bond hydrolysis
Cellular Component
Protein Structure and Domains
PDB ID
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8N9H8
PhosphoSite PhosphoSite-Q8N9H8
TrEMBL E9PI94
UniProt Splice Variant
Entrez Gene 54932
UniGene Hs.495553
RefSeq NP_001273752
HUGO HGNC:26023
OMIM
CCDS CCDS75942
HPRD 07906
IMGT
EMBL AB061798 AK055004 AK094438 BC037355 BC110879 BX322799
GenPept AAH37355 AAI10880 BAB70838 BAC04356 BAC10986 CAX12959

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca