Version 5.4
Homo sapiens Protein: MED23
Summary
InnateDB Protein IDBP-593366.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MED23
Protein Name mediator complex subunit 23
Synonyms ARC130; CRSP130; CRSP133; CRSP3; DRIP130; MRT18; SUR-2; SUR2;
Species Homo sapiens
Ensembl Protein ENSP00000445072
InnateDB Gene IDBG-96537 (MED23)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 67 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Experimentally validated
Total 67 [view]
Protein-Protein 64 [view]
Protein-DNA 3 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003713 transcription coactivator activity
GO:0005515 protein binding
Biological Process
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription from RNA polymerase II promoter
GO:0006367 transcription initiation from RNA polymerase II promoter
GO:0010467 gene expression
Cellular Component
GO:0005654 nucleoplasm
GO:0005667 transcription factor complex
Protein Structure and Domains
PDB ID
InterPro IPR021629 Mediator complex, subunit Med23
PFAM PF11573
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9ULK4
PhosphoSite PhosphoSite-Q9ULK4
TrEMBL
UniProt Splice Variant
Entrez Gene 9439
UniGene Hs.595435
RefSeq
HUGO HGNC:2372
OMIM 605042
CCDS
HPRD 05436
IMGT
EMBL AB033042 AF104255 AF105332 AF135022 AL121575 AL136776 BC060759 CH471051 EU392526
GenPept AAD12724 AAD30202 AAD31729 AAH60759 ACB88854 BAA86530 CAB66710 CAB92072 CAB92073 CAI23319 CAI23320 EAW48052

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca