InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: NUP93

Summary

InnateDB Protein

IDBP-594128.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

NUP93

Protein Name

nucleoporin 93kDa

Synonyms

NIC96;

Species

Homo sapiens

Ensembl Protein

ENSP00000440235

InnateDB Gene

IDBG-32470 (NUP93)

Protein Structure

UniProt Annotation

Function

Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. May anchor nucleoporins, but not NUP153 and TPR, to the NPC. {ECO:0000269PubMed:15229283, ECO:0000269PubMed:15703211}.

Subcellular Localization

Nucleus membrane; Peripheral membrane protein. Nucleus, nuclear pore complex. Note=Localizes at the nuclear basket and at or near the nuclear entry to the gated channel of the pore.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 48 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Experimentally validated
Total	48 [view]
Protein-Protein	48 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0017056	structural constituent of nuclear pore

Biological Process

GO:0000278	mitotic cell cycle
GO:0005975	carbohydrate metabolic process
GO:0006810	transport
GO:0007077	mitotic nuclear envelope disassembly
GO:0008645	hexose transport
GO:0010827	regulation of glucose transport
GO:0015031	protein transport
GO:0015758	glucose transport
GO:0016032	viral process
GO:0019221	cytokine-mediated signaling pathway
GO:0044281	small molecule metabolic process
GO:0051028	mRNA transport
GO:0051292	nuclear pore complex assembly
GO:0055085	transmembrane transport