InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: PTPN1

Summary

InnateDB Protein

IDBP-595103.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PTPN1

Protein Name

protein tyrosine phosphatase, non-receptor type 1

Synonyms

PTP1B;

Species

Homo sapiens

Ensembl Protein

ENSP00000437732

InnateDB Gene

IDBG-80957 (PTPN1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 170 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Experimentally validated
Total	170 [view]
Protein-Protein	167 [view]
Protein-DNA	3 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004725	protein tyrosine phosphatase activity
GO:0016791	phosphatase activity

Biological Process

GO:0006470	protein dephosphorylation
GO:0016311	dephosphorylation
GO:0035335	peptidyl-tyrosine dephosphorylation

Cellular Component

GO:0005783

endoplasmic reticulum

Protein Structure and Domains

PDB ID

InterPro

IPR000242 Protein-tyrosine phosphatase, receptor/non-receptor type
IPR000387 Protein-tyrosine/Dual specificity phosphatase
IPR003595 Protein-tyrosine phosphatase, catalytic
IPR012265 Protein-tyrosine phosphatase, non-receptor type-1/2
IPR029021 Protein-tyrosine phosphatase-like

PFAM

PF00102

PRINTS

PR00700

PIRSF

PIRSF000926

SMART

SM00194
SM00404

TIGRFAMs

Post-translational Modifications

Modification

Cross-References