InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: HADHB

Summary

InnateDB Protein

IDBP-595168.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

HADHB

Protein Name

hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit

Synonyms

ECHB; MTPB; TP-BETA;

Species

Homo sapiens

Ensembl Protein

ENSP00000442665

InnateDB Gene

IDBG-35294 (HADHB)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 59 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	59 [view]
Protein-Protein	56 [view]
Protein-DNA	3 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0003857	3-hydroxyacyl-CoA dehydrogenase activity
GO:0003988	acetyl-CoA C-acyltransferase activity
GO:0005515	protein binding
GO:0016747	transferase activity, transferring acyl groups other than amino-acyl groups
GO:0044822	poly(A) RNA binding

Biological Process

GO:0006635	fatty acid beta-oxidation
GO:0006644	phospholipid metabolic process
GO:0008152	metabolic process
GO:0035965	cardiolipin acyl-chain remodeling
GO:0044255	cellular lipid metabolic process
GO:0044281	small molecule metabolic process
GO:0046474	glycerophospholipid biosynthetic process

Cellular Component

GO:0005739	mitochondrion
GO:0005740	mitochondrial envelope
GO:0005741	mitochondrial outer membrane
GO:0005743	mitochondrial inner membrane
GO:0005783	endoplasmic reticulum
GO:0042645	mitochondrial nucleoid
GO:0070062	extracellular vesicular exosome