Version 5.4
Homo sapiens Protein: HADHB
Summary
InnateDB Protein IDBP-596838.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HADHB
Protein Name hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit
Synonyms ECHB; MTPB; TP-BETA;
Species Homo sapiens
Ensembl Protein ENSP00000444295
InnateDB Gene IDBG-35294 (HADHB)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 59 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 59 [view]
Protein-Protein 56 [view]
Protein-DNA 3 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0016747 transferase activity, transferring acyl groups other than amino-acyl groups
Biological Process
GO:0008152 metabolic process
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR002155 Thiolase
IPR014030 Beta-ketoacyl synthase, N-terminal
IPR016039 Thiolase-like
IPR020616 Thiolase, N-terminal
IPR020617 Thiolase, C-terminal
PFAM PF00109
PF00108
PF02803
PRINTS
PIRSF PIRSF000429
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL F5GZQ3
UniProt Splice Variant
Entrez Gene 3032
UniGene Hs.637424
RefSeq NP_001268441
HUGO HGNC:4803
OMIM 143450
CCDS CCDS62871
HPRD 00887
IMGT
EMBL AC010896
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca