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InnateDB Protein
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IDBP-598450.2
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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SMAD3
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Protein Name
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SMAD family member 3
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Synonyms
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HSPC193; HsT17436; JV15-2; LDS1C; LDS3; MADH3;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000453684
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InnateDB Gene
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IDBG-18366 (SMAD3)
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Protein Structure
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| Function |
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| Subcellular Localization |
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| Disease Associations |
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| Tissue Specificity |
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| Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 529 experimentally validated interaction(s) in this database.
They are also associated with 63 interaction(s) predicted by orthology.
| Experimentally validated |
| Total |
529
[view]
|
| Protein-Protein |
508
[view]
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| Protein-DNA |
16
[view]
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| Protein-RNA |
0
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| DNA-DNA |
5
[view]
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| RNA-RNA |
0
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| DNA-RNA |
0
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| Predicted by orthology |
| Total |
63 [view]
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Molecular Function |
| Accession |
GO Term |
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GO:0003700
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sequence-specific DNA binding transcription factor activity
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| Biological Process |
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GO:0006355
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regulation of transcription, DNA-templated
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GO:0007179
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transforming growth factor beta receptor signaling pathway
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| Cellular Component |
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| PDB ID |
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| InterPro |
IPR003619
MAD homology 1, Dwarfin-type
IPR013019
MAD homology, MH1
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| PFAM |
PF03165
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| PRINTS |
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| PIRSF |
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| SMART |
SM00523
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| TIGRFAMs |
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| Modification |
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| SwissProt |
|
| PhosphoSite |
PhosphoSite-
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| TrEMBL |
H0YMP2
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| UniProt Splice Variant |
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| Entrez Gene |
4088
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| UniGene |
Hs.742270
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| RefSeq |
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| HUGO |
HGNC:6769
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| OMIM |
603109
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| CCDS |
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| HPRD |
08533
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| IMGT |
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| EMBL |
AC012568
AC087482
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| GenPept |
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Version 5.4