Version 5.4
Homo sapiens Protein: ISCU
Summary
InnateDB Protein IDBP-599787.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ISCU
Protein Name iron-sulfur cluster scaffold homolog (E. coli)
Synonyms 2310020H20Rik; HML; hnifU; ISU2; NIFU; NIFUN;
Species Homo sapiens
Ensembl Protein ENSP00000445598
InnateDB Gene IDBG-55391 (ISCU)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005506 iron ion binding
GO:0051536 iron-sulfur cluster binding
Biological Process
GO:0016226 iron-sulfur cluster assembly
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR002871 NIF system FeS cluster assembly, NifU, N-terminal
IPR011339 ISC system FeS cluster assembly, IscU scaffold
PFAM PF01592
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL B4DNC9
UniProt Splice Variant
Entrez Gene 23479
UniGene Hs.615131
RefSeq NP_001288069
HUGO HGNC:29882
OMIM 611911
CCDS
HPRD 14828
IMGT
EMBL AC008119 AK297862 FJ695196
GenPept BAG60191

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca