Version 5.4
Homo sapiens Protein: PXN
Summary
InnateDB Protein IDBP-599799.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PXN
Protein Name paxillin
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000443887
InnateDB Gene IDBG-60317 (PXN)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 236 experimentally validated interaction(s) in this database.
They are also associated with 23 interaction(s) predicted by orthology.
Experimentally validated
Total 236 [view]
Protein-Protein 236 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 23 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0008270 zinc ion binding
Biological Process
GO:0007160 cell-matrix adhesion
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0005925 focal adhesion
Protein Structure and Domains
PDB ID
InterPro IPR001781 Zinc finger, LIM-type
IPR001904 Paxillin
PFAM PF00412
PRINTS PR00832
PIRSF
SMART SM00132
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL F8W1E0
UniProt Splice Variant
Entrez Gene 5829
UniGene Hs.446336
RefSeq XP_005253971
HUGO HGNC:9718
OMIM 602505
CCDS
HPRD
IMGT
EMBL AC004263
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca