Version 5.4
Homo sapiens Protein: DAP3
Summary
InnateDB Protein IDBP-600281.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DAP3
Protein Name death associated protein 3
Synonyms bMRP-10; DAP-3; MRP-S29; MRPS29;
Species Homo sapiens
Ensembl Protein ENSP00000445003
InnateDB Gene IDBG-103299 (DAP3)
Protein Structure
UniProt Annotation
Function Involved in mediating interferon-gamma-induced cell death.
Subcellular Localization Mitochondrion {ECO:0000269PubMed:11162496, ECO:0000269PubMed:20563667}.
Disease Associations
Tissue Specificity Ubiquitous.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 47 experimentally validated interaction(s) in this database.
Experimentally validated
Total 47 [view]
Protein-Protein 45 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0097190 apoptotic signaling pathway
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005739 mitochondrion
GO:0005761 mitochondrial ribosome
GO:0015935 small ribosomal subunit
Protein Structure and Domains
PDB ID
InterPro IPR008092 Ribosomal protein S29, mitochondrial
IPR019368 Ribosomal protein S23/S29, mitochondrial
IPR027417 P-loop containing nucleoside triphosphate hydrolase
PFAM PF10236
PRINTS PR01716
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P51398
PhosphoSite PhosphoSite-P51398
TrEMBL V9GYF7
UniProt Splice Variant
Entrez Gene 7818
UniGene Hs.732416
RefSeq NP_001186780
HUGO HGNC:2673
OMIM 602074
CCDS CCDS55647
HPRD 03646
IMGT
EMBL AB061210 AK293117 AK298201 AK302281 AL162734 BC107487 BC107488 BT019494 CH471121 CR749790 U18321 X83544
GenPept AAA57443 AAI07488 AAI07489 AAV38301 BAB54960 BAF85806 BAG60471 BAG63624 CAA58535 CAH18651 CAH71647 EAW53044 EAW53045 EAW53047 EAW53048 EAW53049 EAW53051

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca