Version 5.4
Homo sapiens Protein: SIGIRR
Summary
InnateDB Protein IDBP-600580.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SIGIRR
Protein Name single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000433022
InnateDB Gene IDBG-16551 (SIGIRR)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 17 experimentally validated interaction(s) in this database.
Experimentally validated
Total 17 [view]
Protein-Protein 17 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0007165 signal transduction
GO:0045087 innate immune response (InnateDB)
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR000157 Toll/interleukin-1 receptor homology (TIR) domain
IPR007110 Immunoglobulin-like domain
PFAM PF01582
PF13676
PRINTS
PIRSF
SMART SM00255
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL C9JFX4
UniProt Splice Variant
Entrez Gene 59307
UniGene Hs.501624
RefSeq XP_005253101
HUGO HGNC:30575
OMIM 605478
CCDS
HPRD 12018
IMGT
EMBL AC138230
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca