Version 5.4
Homo sapiens Protein: MYL6
Summary
InnateDB Protein IDBP-600908.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MYL6
Protein Name myosin, light chain 6, alkali, smooth muscle and non-muscle
Synonyms ESMLC; LC17; LC17-GI; LC17-NM; LC17A; LC17B; MLC-3; MLC1SM; MLC3NM; MLC3SM;
Species Homo sapiens
Ensembl Protein ENSP00000446955
InnateDB Gene IDBG-40095 (MYL6)
Protein Structure
UniProt Annotation
Function Regulatory light chain of myosin. Does not bind calcium.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 43 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 43 [view]
Protein-Protein 43 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003774 motor activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0008307 structural constituent of muscle
GO:0030898 actin-dependent ATPase activity
Biological Process
GO:0006200 ATP catabolic process
GO:0006936 muscle contraction
GO:0007411 axon guidance
GO:0007519 skeletal muscle tissue development
GO:0008152 metabolic process
GO:0030049 muscle filament sliding
Cellular Component
GO:0005829 cytosol
GO:0016020 membrane
GO:0016459 myosin complex
GO:0016461 unconventional myosin complex
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR002048 EF-hand domain
PFAM PF00036
PF13202
PF13405
PRINTS
PIRSF
SMART SM00054
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P60660
PhosphoSite PhosphoSite-P60660
TrEMBL
UniProt Splice Variant
Entrez Gene 4637
UniGene Hs.733233
RefSeq NP_066299
HUGO HGNC:7587
OMIM 609931
CCDS CCDS8906
HPRD 17618
IMGT
EMBL AB046613 BC006781 BC017455 BC071661 BC093066 CR457014 M22918 M22919 M22920 M31212 U02629
GenPept AAA20643 AAA36347 AAA36348 AAA59853 AAA59892 AAA59893 AAH06781 AAH17455 AAH71661 AAH93066 BAB62402 CAG33295

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca