Version 5.4
Homo sapiens Protein: PCTP
Summary
InnateDB Protein IDBP-60105.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PCTP
Protein Name phosphatidylcholine transfer protein
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000325181
InnateDB Gene IDBG-60101 (PCTP)
Protein Structure
UniProt Annotation
Function Catalyzes the transfer of phosphatidylcholine between membranes. Binds a single lipid molecule. {ECO:0000269PubMed:12055623}.
Subcellular Localization Cytoplasm {ECO:0000250}.
Disease Associations
Tissue Specificity Highest expression in liver, placenta, testis, kidney and heart. Low levels in brain and lung. No expression detected in thymus. {ECO:0000269PubMed:10542325}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0008289 lipid binding
GO:0008525 phosphatidylcholine transporter activity
GO:0031210 phosphatidylcholine binding
Biological Process
GO:0006869 lipid transport
GO:0015914 phospholipid transport
Cellular Component
GO:0005829 cytosol
Protein Structure and Domains
PDB ID
InterPro IPR002913 START domain
PFAM PF01852
PRINTS
PIRSF
SMART SM00234
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9UKL6
PhosphoSite PhosphoSite-Q9UKL6
TrEMBL
UniProt Splice Variant
Entrez Gene 58488
UniGene Hs.285218
RefSeq NP_001095872
HUGO HGNC:8752
OMIM 606055
CCDS CCDS45741
HPRD 06927
IMGT
EMBL AC009837 AC091155 AF114430 AF114431 AF114432 AF114433 AF114434 AF114435 AF114436 AF151638 BC005112 BC012084
GenPept AAF02536 AAF08345 AAF08347 AAH05112 AAH12084

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca