InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: GPRC5B

Summary

InnateDB Protein

IDBP-601069.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

GPRC5B

Protein Name

G protein-coupled receptor, family C, group 5, member B

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000442858

InnateDB Gene

IDBG-18080 (GPRC5B)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0001664	G-protein coupled receptor binding
GO:0004930	G-protein coupled receptor activity
GO:0019901	protein kinase binding
GO:0030295	protein kinase activator activity

Biological Process

GO:0007186	G-protein coupled receptor signaling pathway
GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0045666	positive regulation of neuron differentiation
GO:0050729	positive regulation of inflammatory response
GO:0060907	positive regulation of macrophage cytokine production
GO:0061098	positive regulation of protein tyrosine kinase activity
GO:0090263	positive regulation of canonical Wnt signaling pathway

Cellular Component

GO:0005615	extracellular space
GO:0005634	nucleus
GO:0005730	nucleolus
GO:0005886	plasma membrane
GO:0009986	cell surface
GO:0016021	integral component of membrane
GO:0030659	cytoplasmic vesicle membrane
GO:0043231	intracellular membrane-bounded organelle
GO:0070062	extracellular vesicular exosome