Version 5.4
Homo sapiens Protein: TJP3
Summary
InnateDB Protein IDBP-601684.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TJP3
Protein Name tight junction protein 3 (zona occludens 3)
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000439991
InnateDB Gene IDBG-17677 (TJP3)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 8 [view]
Protein-Protein 7 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
Cellular Component
GO:0005634 nucleus
GO:0005923 tight junction
Protein Structure and Domains
PDB ID
InterPro IPR001452 SH3 domain
IPR001478 PDZ domain
IPR005417 Zona occludens protein
IPR005420 Zona occludens protein ZO-3
IPR008144 Guanylate kinase-like
IPR008145 Guanylate kinase/L-type calcium channel beta subunit
IPR011511 Variant SH3 domain
IPR027417 P-loop containing nucleoside triphosphate hydrolase
PFAM PF00018
PF14604
PF00595
PF13180
PF00625
PF07653
PRINTS PR00452
PR01597
PR01600
PIRSF
SMART SM00326
SM00228
SM00072
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O95049
PhosphoSite PhosphoSite-O95049
TrEMBL
UniProt Splice Variant
Entrez Gene 27134
UniGene Hs.25527
RefSeq
HUGO HGNC:11829
OMIM 612689
CCDS
HPRD 18194
IMGT
EMBL AC005954 AC006125 AK091118 AK128237 AK304462 BC108906 CH471139
GenPept AAC72274 AAI08907 BAG52285 BAG54652 BAG65278 EAW69293

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca