Version 5.4
Homo sapiens Protein: SLC12A1
Summary
InnateDB Protein IDBP-603207.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SLC12A1
Protein Name solute carrier family 12 (sodium/potassium/chloride transporters), member 1
Synonyms BSC1; NKCC2;
Species Homo sapiens
Ensembl Protein ENSP00000454178
InnateDB Gene IDBG-10865 (SLC12A1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005215 transporter activity
Biological Process
GO:0006810 transport
GO:0006811 ion transport
GO:0055085 transmembrane transport
Cellular Component
GO:0016020 membrane
Protein Structure and Domains
PDB ID
InterPro IPR002445 Na/K/Cl co-transporter 2
IPR004841 Amino acid permease/ SLC12A domain
IPR013612 Amino acid permease, N-terminal
PFAM PF00324
PF08403
PRINTS PR01209
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL H0YNW0
UniProt Splice Variant
Entrez Gene 6557
UniGene Hs.605373
RefSeq
HUGO HGNC:10910
OMIM 600839
CCDS
HPRD 02908
IMGT
EMBL AC023355 AC066612
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca