Version 5.4
Homo sapiens Protein: HLA-DQB1
Summary
InnateDB Protein IDBP-603290.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HLA-DQB1
Protein Name major histocompatibility complex, class II, DQ beta 1
Synonyms CELIAC1; HLA-DQB; IDDM1;
Species Homo sapiens
Ensembl Protein ENSP00000436686
InnateDB Gene IDBG-81203 (HLA-DQB1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II
GO:0006955 immune response
GO:0019882 antigen processing and presentation
Cellular Component
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0042613 MHC class II protein complex
Protein Structure and Domains
PDB ID
InterPro IPR000353 MHC class II, beta chain, N-terminal
IPR011162 MHC classes I/II-like antigen recognition protein
PFAM PF00969
PRINTS
PIRSF
SMART SM00921
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL T1R348
UniProt Splice Variant
Entrez Gene 3119
UniGene Hs.697652
RefSeq
HUGO HGNC:4944
OMIM 604305
CCDS
HPRD 05054
IMGT
EMBL AF307156 AF506754 AL662789 AY036896 AY950605 AY950606 AY999074 JX842724 KC019985 KC020003 KC020013 KC441504 KC592346 KC748259 KC748262 M22550 M65049
GenPept AAA59709 AAA59821 AAK17123 AAK96012 AAM28883 AAX22135 AAX22136 AAY33733 AFZ94661 AFZ94679 AFZ94689 AGG79760 AGI48717 AGK44334 AGK44337 AGL73154

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca