Homo sapiens Protein: AMELY
Summary
InnateDB Protein IDBP-62.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol AMELY
Protein Name amelogenin, Y-linked
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000215479
InnateDB Gene IDBG-58 (AMELY)
Protein Structure
UniProt Annotation
Function Plays a role in biomineralization. Seems to regulate the formation of crystallites during the secretory stage of tooth enamel development. Thought to play a major role in the structural organization and mineralization of developing enamel.
Subcellular Localization Secreted, extracellular space, extracellular matrix.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0030345 structural constituent of tooth enamel
Biological Process
GO:0007275 multicellular organismal development
GO:0031214 biomineral tissue development
Cellular Component
GO:0005578 proteinaceous extracellular matrix
GO:0031012 extracellular matrix
Protein Structure and Domains
PDB ID
InterPro IPR004116 Amelogenin
PFAM PF02948
PRINTS PR01757
PIRSF
SMART SM00818
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q99218
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 266
UniGene Hs.1238
RefSeq NP_001134
HUGO HGNC:462
OMIM 410000
CCDS CCDS14778
HPRD 02462
IMGT
EMBL AY487421 BC069138 BC074976 BC074977 M55419 M86933 X14439
GenPept AAA51718 AAA62827 AAH69138 AAH74976 AAH74977 AAR39431 CAA32612