Mus musculus Protein: Abcg8
Summary
InnateDB Protein IDBP-621902.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Abcg8
Protein Name ATP-binding cassette, sub-family G (WHITE), member 8
Synonyms 1300003C16Rik; AI114946; sterolin-2;
Species Mus musculus
Ensembl Protein ENSMUSP00000127785
InnateDB Gene IDBG-200717 (Abcg8)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005524 ATP binding
GO:0016887 ATPase activity
GO:0017127 cholesterol transporter activity
GO:0046982 protein heterodimerization activity
Biological Process
GO:0006200 ATP catabolic process
GO:0007584 response to nutrient
GO:0007588 excretion
GO:0010949 negative regulation of intestinal phytosterol absorption
GO:0015914 phospholipid transport
GO:0015918 sterol transport
GO:0033344 cholesterol efflux
GO:0042493 response to drug
GO:0042632 cholesterol homeostasis
GO:0045796 negative regulation of intestinal cholesterol absorption
GO:0055092 sterol homeostasis
Cellular Component
GO:0016020 membrane
GO:0016324 apical plasma membrane
Protein Structure and Domains
PDB ID MGI:1914720
InterPro IPR003439 ABC transporter-like
IPR013525 ABC-2 type transporter
IPR027417 P-loop containing nucleoside triphosphate hydrolase
PFAM PF00005
PF01061
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL E9Q0P2
UniProt Splice Variant
Entrez Gene 67470
UniGene Mm.26581
RefSeq NP_001272934
MGI ID
MGI Symbol Abcg8
OMIM
CCDS CCDS70849
HPRD
IMGT
EMBL AC165360
GenPept