Version 5.4
Mus musculus Protein: Dlg4
Summary
InnateDB Protein IDBP-622168.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Dlg4
Protein Name discs, large homolog 4 (Drosophila)
Synonyms Dlgh4; PSD-95; PSD95; SAP90; SAP90A;
Species Mus musculus
Ensembl Protein ENSMUSP00000134545
InnateDB Gene IDBG-193317 (Dlg4)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 372 experimentally validated interaction(s) in this database.
They are also associated with 84 interaction(s) predicted by orthology.
Experimentally validated
Total 372 [view]
Protein-Protein 372 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 84 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0016188 synaptic vesicle maturation
GO:0035418 protein localization to synapse
GO:0048169 regulation of long-term neuronal synaptic plasticity
Cellular Component
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0005886 plasma membrane
GO:0008021 synaptic vesicle
GO:0014069 postsynaptic density
GO:0016020 membrane
GO:0030054 cell junction
GO:0030425 dendrite
GO:0031234 extrinsic component of cytoplasmic side of plasma membrane
GO:0032281 alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex
GO:0044224 juxtaparanode region of axon
GO:0044300 cerebellar mossy fiber
GO:0044306 neuron projection terminus
GO:0044309 neuron spine
GO:0045202 synapse
GO:0060076 excitatory synapse
GO:0097481 neuronal postsynaptic density
Protein Structure and Domains
PDB ID MGI:1277959
InterPro IPR001452 SH3 domain
IPR008144 Guanylate kinase-like
IPR008145 Guanylate kinase/L-type calcium channel beta subunit
IPR011511 Variant SH3 domain
IPR027417 P-loop containing nucleoside triphosphate hydrolase
PFAM PF00018
PF14604
PF00625
PF07653
PRINTS PR00452
PIRSF
SMART SM00326
SM00072
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL G3UZL5
UniProt Splice Variant
Entrez Gene 13385
UniGene Mm.489451
RefSeq
MGI ID
MGI Symbol Dlg4
OMIM
CCDS
HPRD
IMGT
EMBL AL596185
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca