InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Glg1

Summary

InnateDB Protein

IDBP-622680.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Glg1

Protein Name

golgi apparatus protein 1

Synonyms

AI593353; AW537898; CFR; CFR-1; ESL-1; MG-160; MG160; Selel;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000131355

InnateDB Gene

IDBG-192981 (Glg1)

Protein Structure

UniProt Annotation

Function

Binds fibroblast growth factor (By similarity). Binds E- selectin (cell-adhesion lectin on endothelial cells mediating the binding of neutrophils). {ECO:0000250}.

Subcellular Localization

Cell membrane {ECO:0000269PubMed:9099943}; Single-pass type I membrane protein {ECO:0000269PubMed:9099943}. Golgi apparatus membrane {ECO:0000269PubMed:9099943}; Single-pass type I membrane protein {ECO:0000269PubMed:9099943}. Note=Golgi and microvilli on the cell surface.

Disease Associations

Tissue Specificity

Widely expressed; found in myeloid cells, fibroblasts, colon carcinoma, endothelioma, teratocarcinoma, lymphoma, myeloma.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.

Experimentally validated
Total	12 [view]
Protein-Protein	11 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	7 [view]

Gene Ontology

Molecular Function

Accession

GO Term

Biological Process

GO:0010955	negative regulation of protein processing
GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway
GO:0032330	regulation of chondrocyte differentiation
GO:0060349	bone morphogenesis

Cellular Component

GO:0000139	Golgi membrane
GO:0005794	Golgi apparatus
GO:0005886	plasma membrane
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0031012	extracellular matrix
GO:0070062	extracellular vesicular exosome