InnateDB Protein
|
IDBP-623615.2
|
Last Modified
|
2014-10-13 [Report errors or provide feedback]
|
Gene Symbol
|
Cant1
|
Protein Name
|
calcium activated nucleotidase 1
|
Synonyms
|
5830420C20Rik; Apy1h; D11Bwg0554e; Entpd8; SCAN-1; Shapy;
|
Species
|
Mus musculus
|
Ensembl Protein
|
ENSMUSP00000126919
|
InnateDB Gene
|
IDBG-214641 (Cant1)
|
Protein Structure
|
|
Function |
Calcium-dependent nucleotidase with a preference for UDP. The order of activity with different substrates is UDP > GDP > IDP >> UTP > CDP = GTP = ITP. Has very low activity towards ADP and even lower activity towards ATP. Does not hydrolyze AMP and GMP (By similarity). Involved in proteoglycan synthesis (By similarity). {ECO:0000250}.
|
Subcellular Localization |
Endoplasmic reticulum membrane; Single-pass type II membrane protein. Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Note=Processed form: Secreted. {ECO:0000250}.
|
Disease Associations |
|
Tissue Specificity |
|
Comments |
|
Number of Interactions
|
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
|
Predicted by orthology |
Total |
1 [view]
|
|
|
Molecular Function |
|
Biological Process |
GO:0007165
|
signal transduction
|
GO:0009191
|
ribonucleoside diphosphate catabolic process
|
GO:0030166
|
proteoglycan biosynthetic process
|
GO:0043123
|
positive regulation of I-kappaB kinase/NF-kappaB signaling
|
|
Cellular Component |
|
PDB ID |
MGI:1923275
|
InterPro |
IPR009283
Apyrase
|
PFAM |
PF06079
|
PRINTS |
|
PIRSF |
|
SMART |
|
TIGRFAMs |
|
Modification |
|
SwissProt |
Q8VCF1
|
PhosphoSite |
PhosphoSite-
|
TrEMBL |
|
UniProt Splice Variant |
|
Entrez Gene |
76025
|
UniGene |
Mm.473491
|
RefSeq |
NP_001254520
|
MGI ID |
|
MGI Symbol |
Cant1
|
OMIM |
|
CCDS |
CCDS25702
|
HPRD |
|
IMGT |
|
EMBL |
AK006565
AK017942
AK049879
AK081118
AK085059
AL591404
BC020003
|
GenPept |
AAH20003
BAB24655
BAB31014
BAC33968
BAC38139
BAC39351
CAM23112
|
|
|