InnateDB Protein
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IDBP-623700.2
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Tmem8b
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Protein Name
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transmembrane protein 8B
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Synonyms
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000129760
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InnateDB Gene
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IDBG-265760 (Tmem8b)
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Protein Structure
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Function |
May function as a regulator of the EGFR pathway. Probable tumor suppressor which may function in cell growth, proliferation and adhesion (By similarity). {ECO:0000250}.
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Subcellular Localization |
Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. Mitochondrion {ECO:0000250}. Endoplasmic reticulum {ECO:0000250}. Note=Also detected in mitochondrion and endoplasmic reticulum. {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
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Predicted by orthology |
Total |
1 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:2441680
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InterPro |
IPR021910
Protein of unknown function DUF3522
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PFAM |
PF12036
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
B1AWJ5
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PhosphoSite |
PhosphoSite-B1AWJ5
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
242409
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UniGene |
Mm.171489
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RefSeq |
XP_006537973
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MGI ID |
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MGI Symbol |
Tmem8b
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OMIM |
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CCDS |
CCDS51168
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HPRD |
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IMGT |
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EMBL |
AL732626
BC147569
BC147574
BC151067
BC151070
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GenPept |
AAI47570
AAI47575
AAI51068
AAI51071
CAM17054
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