Version 5.4
Mus musculus Protein: Ptpn4
Summary
InnateDB Protein IDBP-624651.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ptpn4
Protein Name protein tyrosine phosphatase, non-receptor type 4
Synonyms hPTP-MEG; Ptn4; PTPMEG; TEP; TEP/mPTPMEG;
Species Mus musculus
Ensembl Protein ENSMUSP00000127713
InnateDB Gene IDBG-187609 (Ptpn4)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 17 interaction(s) predicted by orthology.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 17 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004726 non-membrane spanning protein tyrosine phosphatase activity
GO:0005515 protein binding
GO:0008092 cytoskeletal protein binding
Biological Process
GO:0035335 peptidyl-tyrosine dephosphorylation
Cellular Component
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0019898 extrinsic component of membrane
Protein Structure and Domains
PDB ID MGI:1099792
InterPro IPR000299 FERM domain
IPR000798 Ezrin/radixin/moesin like
IPR001478 PDZ domain
IPR014847 FERM adjacent (FA)
IPR018979 FERM, N-terminal
IPR018980 FERM, C-terminal PH-like domain
IPR019748 FERM central domain
IPR019749 Band 4.1 domain
IPR019750 Band 4.1 family
IPR029071 Ubiquitin-related domain
PFAM PF00595
PF13180
PF08736
PF09379
PF09380
PF00373
PRINTS PR00661
PR00935
PIRSF
SMART SM00228
SM00295
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL E9Q0S8
UniProt Splice Variant
Entrez Gene 19258
UniGene
RefSeq
MGI ID
MGI Symbol Ptpn4
OMIM
CCDS
HPRD
IMGT
EMBL AC123955 AC124760
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca