InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: ACTR1B

Summary

InnateDB Protein

IDBP-62479.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ACTR1B

Protein Name

ARP1 actin-related protein 1 homolog B, centractin beta (yeast)

Synonyms

ARP1B; CTRN2; PC3;

Species

Homo sapiens

Ensembl Protein

ENSP00000289228

InnateDB Gene

IDBG-62477 (ACTR1B)

Protein Structure

UniProt Annotation

Function

Component of a multi-subunit complex involved in microtubule based vesicle motility. It is associated with the centrosome.

Subcellular Localization

Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 28 experimentally validated interaction(s) in this database.

Experimentally validated
Total	28 [view]
Protein-Protein	28 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0005524	ATP binding

Biological Process

GO:0019886

antigen processing and presentation of exogenous peptide antigen via MHC class II

Cellular Component

GO:0005737	cytoplasm
GO:0005813	centrosome
GO:0005829	cytosol
GO:0005869	dynactin complex
GO:0016020	membrane
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR004000 Actin-related protein

PFAM

PF00022

PRINTS

PR00190

PIRSF

SMART

SM00268

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

P42025

PhosphoSite

PhosphoSite-P42025

TrEMBL

UniProt Splice Variant

Entrez Gene

10120

UniGene

Hs.98791

RefSeq

NP_005726

HUGO

HGNC:168

OMIM

605144

CCDS

CCDS2033

HPRD

05508

IMGT

EMBL

AC017099 BC004374 BC006372 BC010090 CH471127 X82207

GenPept

AAH04374 AAH06372 AAH10090 AAY24280 CAA57691 EAX01924 EAX01927