InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Marveld2

Summary

InnateDB Protein

IDBP-625474.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Marveld2

Protein Name

MARVEL (membrane-associating) domain containing 2

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000126438

InnateDB Gene

IDBG-178158 (Marveld2)

Protein Structure

UniProt Annotation

Function

Plays a role in the formation of the epithelial barriers. The separation of the endolymphatic and perilymphatic spaces of the organ of Corti from one another by epithelial barriers is required for normal hearing. {ECO:0000269PubMed:16365161}.

Subcellular Localization

Cell membrane; Multi-pass membrane protein. Cell junction, tight junction. Note=Found at tricellular contacts.

Disease Associations

Tissue Specificity

Predominently localized to small intestine, stomach and kidney, in epithelial cells. {ECO:0000269PubMed:16365161}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function

Biological Process

GO:0007605	sensory perception of sound
GO:0045216	cell-cell junction organization

Cellular Component

GO:0005886	plasma membrane
GO:0005923	tight junction
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0033010	paranodal junction
GO:0043220	Schmidt-Lanterman incisure