Version 5.4
Mus musculus Protein: Ndufaf2
Summary
InnateDB Protein IDBP-626465.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ndufaf2
Protein Name NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 2
Synonyms 1810058I14Rik; C86051; mimitin; Ndufa12l;
Species Mus musculus
Ensembl Protein ENSMUSP00000130532
InnateDB Gene IDBG-181431 (Ndufaf2)
Protein Structure
UniProt Annotation
Function Acts as a molecular chaperone for mitochondrial complex I assembly. {ECO:0000250}.
Subcellular Localization Mitochondrion {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0008137 NADH dehydrogenase (ubiquinone) activity
Biological Process
GO:0022904 respiratory electron transport chain
GO:0045333 cellular respiration
GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus
GO:0072593 reactive oxygen species metabolic process
Cellular Component
GO:0005739 mitochondrion
Protein Structure and Domains
PDB ID MGI:1922847
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q59J78
PhosphoSite PhosphoSite-Q59J78
TrEMBL
UniProt Splice Variant
Entrez Gene 75597
UniGene
RefSeq NP_001120818
MGI ID
MGI Symbol Ndufaf2
OMIM
CCDS CCDS49357
HPRD
IMGT
EMBL AB183434 AY262012 BC116975 BC116977
GenPept AAI16976 AAI16978 AAP33449 BAD91206

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca