InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Akap13

Summary

InnateDB Protein

IDBP-627102.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Akap13

Protein Name

A kinase (PRKA) anchor protein 13

Synonyms

1700026G02Rik; 5730522G15Rik; 5830460E08Rik; AKAP-Lbc; BRX; Ht31; LBC; PROTO-LB; PROTO-LBC;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000129784

InnateDB Gene

IDBG-193054 (Akap13)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 24 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	0
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	24 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004691	cAMP-dependent protein kinase activity
GO:0005089	Rho guanyl-nucleotide exchange factor activity
GO:0017048	Rho GTPase binding
GO:0032947	protein complex scaffold
GO:0046872	metal ion binding
GO:0051018	protein kinase A binding

Biological Process

GO:0006468	protein phosphorylation
GO:0010611	regulation of cardiac muscle hypertrophy
GO:0032319	regulation of Rho GTPase activity
GO:0035023	regulation of Rho protein signal transduction
GO:0035556	intracellular signal transduction
GO:0045859	regulation of protein kinase activity
GO:0051168	nuclear export
GO:1900169	regulation of glucocorticoid mediated signaling pathway

Cellular Component

GO:0048471

perinuclear region of cytoplasm

Protein Structure and Domains

PDB ID

MGI:2676556

InterPro

IPR000219 Dbl homology (DH) domain
IPR001849 Pleckstrin homology domain
IPR002219 Protein kinase C-like, phorbol ester/diacylglycerol binding
IPR020683 Ankyrin repeat-containing domain

PFAM

PF00621
PF00169
PF00130
PF11929
PF12796

PRINTS

PIRSF

SMART

SM00325
SM00233
SM00109

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite