InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: CD83

Summary

InnateDB Protein

IDBP-62752.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

CD83

Protein Name

CD83 molecule

Synonyms

BL11; HB15;

Species

Homo sapiens

Ensembl Protein

ENSP00000368450

InnateDB Gene

IDBG-62750 (CD83)

Protein Structure

UniProt Annotation

Function

May play a significant role in antigen presentation or the cellular interactions that follow lymphocyte activation.

Subcellular Localization

Membrane; Single-pass type I membrane protein.

Disease Associations

Tissue Specificity

Expressed by activated lymphocytes, Langerhans cells and interdigitating reticulum cells.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	10 [view]
Protein-Protein	3 [view]
Protein-DNA	6 [view]
Protein-RNA	1 [view]
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding

Biological Process

GO:0006952	defense response
GO:0006959	humoral immune response
GO:0007165	signal transduction
GO:0014070	response to organic cyclic compound
GO:0032713	negative regulation of interleukin-4 production
GO:0032733	positive regulation of interleukin-10 production
GO:0032743	positive regulation of interleukin-2 production
GO:0043372	positive regulation of CD4-positive, alpha-beta T cell differentiation