Version 5.4
Homo sapiens Protein: PRRG2
Summary
InnateDB Protein IDBP-63081.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PRRG2
Protein Name proline rich Gla (G-carboxyglutamic acid) 2
Synonyms PRGP2;
Species Homo sapiens
Ensembl Protein ENSP00000246794
InnateDB Gene IDBG-63079 (PRRG2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Membrane; Single-pass type I membrane protein.
Disease Associations
Tissue Specificity Highly expressed in the thyroid.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 6 [view]
Protein-Protein 5 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
GO:0005515 protein binding
Biological Process
Cellular Component
GO:0005576 extracellular region
GO:0005887 integral component of plasma membrane
Protein Structure and Domains
PDB ID
InterPro IPR000294 Gamma-carboxyglutamic acid-rich (GLA) domain
PFAM PF00594
PRINTS PR00001
PIRSF
SMART SM00069
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O14669
PhosphoSite PhosphoSite-O14669
TrEMBL M0QXL9
UniProt Splice Variant
Entrez Gene 5639
UniGene Hs.35101
RefSeq NP_000942
HUGO HGNC:9470
OMIM 604429
CCDS CCDS12773
HPRD 09189
IMGT
EMBL AC010619 AF009243 CR456846
GenPept AAB67071 CAG33127

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca