InnateDB Protein
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IDBP-63191.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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ARL6IP4
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Protein Name
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ADP-ribosylation-like factor 6 interacting protein 4
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000350532
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InnateDB Gene
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IDBG-63187 (ARL6IP4)
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Protein Structure
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Function |
Involved in modulating alternative pre-mRNA splicing with either 5' distal site activation or preferential use of 3' proximal site. In case of infection by Herpes simplex virus (HSVI), may act as a splicing inhibitor of HSVI pre-mRNA. {ECO:0000269PubMed:19582790}.
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Subcellular Localization |
Nucleus, nucleolus {ECO:0000269PubMed:19582790}. Nucleus speckle {ECO:0000269PubMed:19582790}.
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Disease Associations |
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Tissue Specificity |
Isoforms 3 and 7 were identified in brain, pancreas, prostate, and testis, but little or no message could be detected in other tissues. {ECO:0000269PubMed:19582790}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated |
Total |
12
[view]
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Protein-Protein |
11
[view]
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Protein-DNA |
1
[view]
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
2 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR019532
Nuclear RNA-splicing-associated protein, SR-25
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PFAM |
PF10500
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q66PJ3
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PhosphoSite |
PhosphoSite-Q66PJ3
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
51329
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UniGene |
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RefSeq |
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HUGO |
HGNC:18076
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OMIM |
607668
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CCDS |
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HPRD |
09640
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IMGT |
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EMBL |
AB035384
AC026362
AF267748
BC001958
BC015569
BC015909
BC094839
CH471054
DQ099385
EF036485
EU624490
EU624491
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GenPept |
AAF76892
AAH01958
AAH15569
AAH15909
AAH94839
AAZ13761
ABO65071
ACF07995
ACF07996
BAA94744
EAW98374
EAW98376
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