Version 5.4
Homo sapiens Protein: AQP11
Summary
InnateDB Protein IDBP-65648.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol AQP11
Protein Name aquaporin 11
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000318770
InnateDB Gene IDBG-65646 (AQP11)
Protein Structure
UniProt Annotation
Function Aquaporins facilitate the transport of water and small neutral solutes across cell membranes. {ECO:0000250}.
Subcellular Localization Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005215 transporter activity
GO:0015250 water channel activity
Biological Process
GO:0001822 kidney development
GO:0006810 transport
GO:0006833 water transport
GO:0048388 endosomal lumen acidification
GO:0051260 protein homooligomerization
GO:0055085 transmembrane transport
GO:0072014 proximal tubule development
Cellular Component
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0009986 cell surface
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0030425 dendrite
Protein Structure and Domains
PDB ID
InterPro IPR000425 Major intrinsic protein
IPR016697 Aquaporin 11/12
IPR023266 Aquaporin 11
IPR023271 Aquaporin-like
PFAM PF00230
PRINTS PR00783
PR02024
PIRSF PIRSF017529
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8NBQ7
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 282679
UniGene Hs.668696
RefSeq NP_766627
HUGO HGNC:19940
OMIM 609914
CCDS CCDS8251
HPRD 16503
IMGT
EMBL AB028147 AK075346 BC040443
GenPept AAH40443 BAC11558 BAC45004

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca