Version 5.4
| Homo sapiens Protein: FPR3 | |||||||||
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| Summary | |||||||||
| InnateDB Protein | IDBP-66338.5 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | FPR3 | ||||||||
| Protein Name | formyl peptide receptor 3 | ||||||||
| Synonyms | FML2_HUMAN; FMLPY; FPRH1; FPRH2; FPRL2; RMLP-R-I; | ||||||||
| Species | Homo sapiens | ||||||||
| Ensembl Protein | ENSP00000341821 | ||||||||
| InnateDB Gene | IDBG-66336 (FPR3) | ||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||
| Function | Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. | ||||||||
| Subcellular Localization | Cell membrane; Multi-pass membrane protein. | ||||||||
| Disease Associations | |||||||||
| Tissue Specificity | |||||||||
| Comments | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||
| PDB ID | |||||||||
| InterPro |
IPR000276
G protein-coupled receptor, rhodopsin-like IPR002234 Anaphylatoxin chemotactic receptor family IPR017452 GPCR, rhodopsin-like, 7TM |
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| PFAM |
PF00001
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| PRINTS |
PR00237
PR01104 |
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| PIRSF | |||||||||
| SMART | |||||||||
| TIGRFAMs | |||||||||
| Post-translational Modifications | |||||||||
| Modification | |||||||||
| Cross-References | |||||||||
| SwissProt | P25089 | ||||||||
| PhosphoSite | PhosphoSite- | ||||||||
| TrEMBL | Q6L5J4 | ||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 2359 | ||||||||
| UniGene | Hs.445466 | ||||||||
| RefSeq | NP_002021 | ||||||||
| HUGO | HGNC:3828 | ||||||||
| OMIM | 136539 | ||||||||
| CCDS | CCDS12841 | ||||||||
| HPRD | 00648 | ||||||||
| IMGT | |||||||||
| EMBL | AC005946 AK292541 AY262690 BC059388 BC069070 BC069593 BC069812 CH471135 L14061 M76673 | ||||||||
| GenPept | AAA52474 AAA58482 AAC72102 AAH59388 AAH69070 AAH69593 AAH69812 AAP20654 BAF85230 EAW72045 | ||||||||