InnateDB Protein
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IDBP-6664.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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CDC42EP1
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Protein Name
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CDC42 effector protein (Rho GTPase binding) 1
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Synonyms
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BORG5; CEP1; MSE55;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000249014
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InnateDB Gene
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IDBG-6662 (CDC42EP1)
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Protein Structure
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Function |
Probably involved in the organization of the actin cytoskeleton. Induced membrane extensions in fibroblasts. {ECO:0000269PubMed:10430899}.
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Subcellular Localization |
Endomembrane system {ECO:0000269PubMed:10430899}; Peripheral membrane protein {ECO:0000269PubMed:10430899}. Cytoplasm, cytoskeleton {ECO:0000269PubMed:10430899}.
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Disease Associations |
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Tissue Specificity |
Endothelial and bone marrow stromal cells.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated |
Total |
13
[view]
|
Protein-Protein |
13
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
1 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR000095
CRIB domain
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PFAM |
PF00786
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PRINTS |
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PIRSF |
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SMART |
SM00285
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TIGRFAMs |
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Modification |
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SwissProt |
Q00587
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PhosphoSite |
PhosphoSite-Q00587
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TrEMBL |
B0QYC8
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UniProt Splice Variant |
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Entrez Gene |
11135
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UniGene |
Hs.594639
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RefSeq |
NP_689449
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HUGO |
HGNC:17014
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OMIM |
606084
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CCDS |
CCDS13949
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HPRD |
07303
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IMGT |
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EMBL |
AK292190
AL022315
BC009356
CH471095
CR456524
M88338
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GenPept |
AAA36606
AAH09356
BAF84879
CAB42833
CAG30410
EAW60164
EAW60165
EAW60166
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