Version 5.4
Homo sapiens Protein: OSCAR
Summary
InnateDB Protein IDBP-68001.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol OSCAR
Protein Name osteoclast associated, immunoglobulin-like receptor
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000304523
InnateDB Gene IDBG-67991 (OSCAR)
Protein Structure
UniProt Annotation
Function Regulator of osteoclastogenesis which plays an important bone-specific function in osteoclast differentiation. {ECO:0000250}.
Subcellular Localization Isoform 1: Secreted {ECO:0000305}.Isoform 2: Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR003599 Immunoglobulin subtype
PFAM
PRINTS
PIRSF
SMART SM00409
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8IYS5
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 126014
UniGene Hs.347655
RefSeq NP_573398
HUGO HGNC:29960
OMIM 606862
CCDS CCDS12874
HPRD 06035
IMGT
EMBL AC012314 AF251702 AF391162 AF391163 AF391164 AF474152 AF474153 AK091111 AK130199 AX746784 BC035023
GenPept AAH35023 AAL68495 AAL68496 AAL68497 AAM19095 AAQ05766 AAQ05767 BAC03586

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca