Version 5.4
| Bos taurus Protein: CCT8 | |||||||||
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| Summary | |||||||||
| InnateDB Protein | IDBP-681673.2 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | CCT8 | ||||||||
| Protein Name | T-complex protein 1 subunit theta | ||||||||
| Synonyms | |||||||||
| Species | Bos taurus | ||||||||
| Ensembl Protein | ENSBTAP00000018917 | ||||||||
| InnateDB Gene | IDBG-630232 (CCT8) | ||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||
| Function | Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Known to play a role, in vitro, in the folding of actin and tubulin (By similarity). {ECO:0000250}. | ||||||||
| Subcellular Localization | Cytoplasm {ECO:0000250}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250}. | ||||||||
| Disease Associations | |||||||||
| Tissue Specificity | |||||||||
| Comments | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 84 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||
| PDB ID | |||||||||
| InterPro |
IPR002423
Chaperonin Cpn60/TCP-1 IPR012721 T-complex protein 1, theta subunit IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) IPR027409 GroEL-like apical domain |
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| PFAM |
PF00118
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| PRINTS |
PR00304
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| PIRSF | |||||||||
| SMART | |||||||||
| TIGRFAMs | |||||||||
| Post-translational Modifications | |||||||||
| Modification | |||||||||
| Cross-References | |||||||||
| SwissProt | Q3ZCI9 | ||||||||
| PhosphoSite | PhosphoSite- | ||||||||
| TrEMBL | |||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 281047 | ||||||||
| UniGene | Bt.49440 | ||||||||
| RefSeq | NP_001028781 | ||||||||
| HUGO | |||||||||
| OMIM | |||||||||
| CCDS | |||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | BC102169 | ||||||||
| GenPept | AAI02170 | ||||||||